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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a0d1330393a34d83efe431f4f5fbc8d47abb272f2bac38a5d6597b1d4e0908b' 
  AND token = 'ZkX2y24GllGKqVbg/soRjVG0m6wI3aPCJ2OxZCR2tb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}