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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ed45e689f51ae707ea348e0275909cfc767298a3ffcf2ff65b6d238f550cac' 
  AND token = 'As/oTzhY5MEuInXhJgTb7bie9RJcgzP9IH0QYxg55LA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}