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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0af4e0ddac4b129b57985160b7fc67b61f006c3758a2e15913e1122fd204561' 
  AND token = 'faNabnO/eqVI0MhfLarrfG6vacqaVvZQef9e9Bn5bnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}