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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fa52f8561537aa3746aacfd4042eb5dbbf9ef2ef53fd9b4156f36723865736f' 
  AND token = 'u4akwREdD0REM3fTZkaevsutTWOufZuC6GY7oP8g8VA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}