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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccf2ba80bce83127498042d520387bb1d1f8094d26d552390c721e3a0ed7ee1c' 
  AND token = 'Z+DF5W6HQRXNF/FhIKId6JTre2aDgMoq4k/bv2ktgw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}