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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1ee53291c1c7445f52d9f45c621664963092a09a6282d919aac7de354c16d6c' 
  AND token = 'Fi8RqVEWl2Nne5rwIkJ7/0TpIDtpQ18CCX7gumyYn0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}