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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53079ad26a21c2ef5cafc83418c9d644eccbdf57f3afe8f549289ac338eea65c' 
  AND token = 'v/QQA8r5rIO98u/x1TLAt/WZNNv1ybH2GB3nPSsFJBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}