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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef3d6fc98a714680198a4c3e6b087747b0a9047a4fed79864307adbc389578f0' 
  AND token = 'l5TDftQLTO6QwbHq6OZRAhlPdh+D10enaX7+MGP3fFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}