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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6f4fc4a7de3ea927c4c06c6c36d94a3723e8b718c851664d847936461a72f22' 
  AND token = 'rbDD03QPnv/+efgh4MThEoySTBfOY8REAqL7vlo8zBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}