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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '181fa95fdc2dfed140ec1f76402d1fc2e477255b1a4246a66508c5cc8688e8e5' 
  AND token = 'bQNSpjUwh8u0/z5oMYRTmhTrSLnXVu/k5RNOc1gmMwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}