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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bac56c09f8e28bc017fd7c7f0afefefdc05a80ef32bfab6e3ce3e6e977f1305' 
  AND token = 'c8dDeRHfxY2Cbty2jd+RE7Pk1BT2IRVsU5VKwRBGIo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}