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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f180222b3a5d34cea3015ad21effe29b9a111f82d1b82ca153e571a938efa87' 
  AND token = 'Uy4a4ksav41H10WBENxpLo28WUFFvcGGAazQk4pytRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00008

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}