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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '379bc1a562c89ad331f70a577ae06c500a04a4b99544d96b65f1f2761b196de4' 
  AND token = 'Pz4r84Ur6hVp4nS/qCyGjmoZPtJIhH154RcrWjPhKpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}