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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21e4049881b81816c2b3a5a9ebb41a096f94698aa97205fbf0035a72108b1aee' 
  AND token = 'FbwM5hyknVAgvJiIcavnht7Ur/xQLy8YE9sYyE/FBOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}