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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a379cc163c7d2af46175bb6835e78ee78e323bebe0289ad4228e73e555476ac9' 
  AND token = 'To33QDJ5XUsiHm/3y7jXmkTYjE3euxRQg16EgC5u14c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}