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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b3b214699033a3e9106b3e20aa2e5d1a86a9475743e88d5380617cbc1355683' 
  AND token = 'ORx/StmcDbAkbIRbVLg2Xk7G1FKMw8Os4cNmUoKvyC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}