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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bc8b33d599612f6a330b37d9d4a8d15803706ecd763f2603f1327b44d3c394c' 
  AND token = 'gIeyO+ltNQ97kTzij/hl4zLYNhaCblYLpQQMMBpetfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}