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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35a0df20eaac492d50476d8202d25bd7ff7b51b80fd60d0d1bca10d22cfa5662' 
  AND token = 'FovRHNn8pOTwreQd1/i4QkTM9CjVBL1u8txfdjVRZC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}