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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3291af9afc4c1c02a45b9815dd0d5deeb0b8247291a43c813cbc57282511afd9' 
  AND token = '+5y1/stggfy7XgINRW9tKxjvV567AtwV1kKz4IexsCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00007

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}