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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e81e25b818d72e5aab356a1bd18a99c24f82022d8fe683ac24e3d08b4ca2df25' 
  AND token = 'ir2RZrIhfiwAuHgl26j/WE8Hu3GGkbWZlIPdbJhqG24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}