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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4557b74e390e5d3fe810f9989a97d26756068e3ee7306a6bb4d185744b38ed8a' 
  AND token = 'Jk7UjCUMtt7a81/+nk5IJ0QmeTfd1Aqlm9q4jzc/ppM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00007

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}