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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '521a854d3c075033766c82c324bc09a9ce1b54d19fda3f17e06b1a3889732c2a' 
  AND token = 'fekG195n6Trwgh8z7KUl6teZSSHI3K/pApz9WoTc+gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}