SELECT 
  b.variant_name, 
  a.* 
FROM 
  cscart_product_option_variants AS a 
  LEFT JOIN cscart_product_option_variants_descriptions AS b ON b.variant_id = a.variant_id 
  AND b.lang_code = 'en' 
WHERE 
  1 
  AND a.option_id IN (
    32, 201, 153, 195, 180, 182, 50, 52, 9, 
    44, 46, 170, 190, 184, 209, 210
  ) 
  AND a.status = 'A' 
ORDER BY 
  a.position, 
  a.variant_id

Query time 0.00112

JSON explain

{
  "query_block": {
    "select_id": 1,
    "read_sorted_file": {
      "filesort": {
        "sort_key": "a.position, a.variant_id",
        "table": {
          "table_name": "a",
          "access_type": "ALL",
          "possible_keys": ["status", "option_id", "option_id_2"],
          "rows": 352,
          "filtered": 34.375,
          "attached_condition": "a.option_id in (32,201,153,195,180,182,50,52,9,44,46,170,190,184,209,210) and a.`status` = 'A'"
        }
      }
    },
    "table": {
      "table_name": "b",
      "access_type": "eq_ref",
      "possible_keys": ["PRIMARY"],
      "key": "PRIMARY",
      "key_length": "9",
      "used_key_parts": ["variant_id", "lang_code"],
      "ref": ["multi_vendor.a.variant_id", "const"],
      "rows": 1,
      "filtered": 100,
      "attached_condition": "trigcond(b.lang_code = 'en')"
    }
  }
}