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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a18ce4893131834c5e1817e451984304deb32c0064b2fe62a0d44527ff5bf5b5' 
  AND token = 'NY6Vs0TZTW4P2rwK0f6pOpMJuzhuoXig+DM5XCEXfzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00008

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}