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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50e874364114c5256fef16d4344dbce901207327b60aaf8a7b6f086d49e98638' 
  AND token = 'Rb1UdtbKDProtR72lpvTUdq6ix0yM8AWTF1gq68qhnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}