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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6c0150207cd3fac7e8551fabc325a66af346a0a91184b7e8751bfc13f008686' 
  AND token = '21Q2ypFjuzWsJL07A9+Avn6TkfLebiUa1Sj+cb4BHS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}