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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99a33d54d687d40a0d40f0f7d50760a35eec5f42d00eb3f1bc1748cbfedff147' 
  AND token = 'cihhIYcrK33CPl3fMEg3/XYrj2rVVEX08gbQvPgU/zY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}