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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65ed11736846e8728332950a5041bf34f37df7c32fe8968128144ad7db0c5f61' 
  AND token = '1C9Rkm3AkDjXx1+0ZdaSl+OvjMW/YDQ8TW7ZpJLf40Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}